Hibernating Myocardium

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Hibernating myocardium.

Decreased myocardial contraction occurs as a consequence of a reduction in blood flow. The concept of hibernation implies a downregulation of contractile function as an adaptation to a reduction in myocardial blood flow that serves to maintain myocardial integrity and viability during persistent ischemia. Unequivocal evidence for this concept exists in scenarios of myocardial ischemia that last...

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Hibernating myocardium: new answers, still more questions!

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Hibernating myocardium: diagnosis and patient outcomes.

Approximately 50% of the patients with chronic obstructive coronary artery disease resulting in chronic contractile dysfunction have hibernating myocardium and may benefit from revascularization. This pooled analysis describes the relative merits of dobutamine echocardiography, thallium-201 and technetium-99m scintigraphy, positron emission tomography, and magnetic resonance imaging, for the di...

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ژورنال

عنوان ژورنال: Circulation Research

سال: 2008

ISSN: 0009-7330,1524-4571

DOI: 10.1161/circresaha.107.168278